US Centers for Disease Control and Prevention report that immunisation strategies for infants, children, and adolescents have been implemented with considerable success.

"Recent estimates indicate that approximately 95% of pregnant women are tested for HBsAg and that case management has been effective in ensuring high levels of initiation and completion of postexposure immunoprophylaxis among infants born to HBsAg-positive women".

"Hepatitis B vaccine has been integrated successfully into the childhood vaccination schedule, and infant vaccination coverage levels now are equivalent to those of other vaccines in the childhood schedule".

"Vaccination coverage among adolescents also has increased substantially; preliminary data from 2003 indicated that approximately 50%-60% of adolescents aged 13--15 years have records indicating vaccination (with 3 doses) against hepatitis B".

"During 1990-2005, incidence of acute hepatitis B in the United States declined 78%. The greatest decline (96%) occurred among children and adolescents, coincident with an increase in hepatitis B vaccination coverage. This success can be attributed in part to the established infrastructure for vaccine delivery to children and to federal support for perinatal hepatitis B prevention programs".