does anyone know whether entecavir is appropriate for all hepB? my partner who is HepB (not in this country) has not been told about this drug.I know it has recently been approved in the UK.. she will prob need to go into treatment soon as the trans ..
Hi Mary,
im on inteferon at the moment. The last time i went to my consultant, i enquired about Entecavir, it was bought up in the other thread, so i thought i'd ask about it. Anyway, basically i was told If the Interferon doesn't work i would be pu..
I am not a doctor and so this is only my own view but all that I have read these last two years and the latest research shows that lamivudine while being effective and working fine for some does have a relatively high level of drug resistance as th..
Hi, Brit, yes, you are very lucky there in Holland, i am just wandering if anybody in England was prescribed Entecavir yet and what would be a cost of the private treatment?
Also, did anybody do biopsy before any treatment(such as lamivudine, interf..
Hi Lisa,
I am in England and am on Peg Interferon at the moment. I had a biopsy and scan before this was prescribed, and also my usual LFT's. My viral load is high, so that is prob why they prescribed the Peg Interferon first.
I have asked about E..
Hi, Lily, this website has got "contact us " section with their telephon numbers and e-mail. Perhaps, its a good idea to contact them for some advise. After all it was this website stating "Entecavir is approved in UK now" - anyway ,just a thought
..
hi Lisa and Lily
Lily's post about the hospital not wishing to prescribe it on the basis of costs is quite worrying to read. I really wonder how much the hospital/specialists know about about the resistance profile of the drug lamivudine. Lamivduine..
Hey Brit,
How are you? Ive emailed th site and they are looking into it for me at the moment to see where exactly the government stands at the moment with Entecavir, so fingers crossed. :o) ..
Hi Lily,
fine thanks.
I wish you good luck with this. I hope you get access to the drug. You should do....as you rightly said ....hospital budget considerations should not simply override everything else if the drug is approved (or am I being naive..
Lily,
read this today on the American HBV Advocate Website. I think the figures speak for themselves - maybe you should show your specialist this:
www.hbvadvocate.org/hepatitis/hepB/antiviral_first.html
..
Hi Brit / lily,
I hope you're both well, I haven't been around to post recently. Brit, thanks for posting that article on drug resistance. It's fascinating and is a real eye-opener. My first drug was Lamivudine which i mutated past. Then Adefovi..
Hey Brit/Simon,
Well, i got a reply from the Foundation today regarding the Entecavir.Good news! (Simon, you might find this interesting if your looking at new treatment).Basically, i have the right as a patient to choose WHERE i get treatment, ther..
Hi Lily,
Thanks for the info. You just confirmed what I thought because, I live in London and UCH is where I go anyway. UCL is now part of UCH, they are all one now.
When I last saw my consultant he did say it was possible to get the newer drugs,..
Lily,
Please remind me. You're on the Peg aren't you? How long have you been on it for and do you get bad side effects. Apparently when Peg works it really does work.
sm..
Hi, guys, can anybody tell me where and when is PCR DNA (viral load ) blood test taken? When i asked my GP to do that, hi had no idea about all this! Next week we are seeing some consultant in London- should i ask him to do this blood test? Thank you..
Hi Lisa,
The PCR DNA test for viral load will done when you see your consultant. They will probably do it every time you go to see them.
It's very rare, in fact probably impossible, for your GP to order this test from your local surgery. It's an ..
Hi all! I'm concerned that people are being given lamivudine just because it's cheap and doctors are "made" to give it. A doctor is at liberty to prescribe whatever he likes unless the hospital forbids it. If the hospital will only let you be given l..
Have you heard about tenofivir? It is an HIV drug that has started to be used in the USA for HepB. I've heard it is probably the best there is right now for su amongst the antivirals. I suggest it is worth talking to your doctor about it if you are c..
Have you heard about tenofivir? It is an HIV drug that has started to be used in the USA for HepB. I've heard it is probably the best there is right now for su amongst the antivirals. I suggest it is worth talking to your doctor about it if you are c..
Hi Ian (and everyone else
I agree with all your comments - Tenofivir is looking very promising for Hep B in the future and the results so far make it one of the best. Interesting to read that there is a way to try and get access to it in the UK .
..
Hi Everyone!
Sorry haven't posted in a while. Feeling a bit nervous at the moment, i am coming up to the end of my fourth month on the Peg Interferon. My consultant told me they will be able to tell wether it's working or not at the ned of the fourt..
Hi Lily,
I really hope it's working for you, please let us know, I'm really interested.
I went to UCH to see my liver consulant last week and my results were pretty good actually. I've been on Lamivudine and adefovir since November and my viral lo..
Lily,
I know all too well that anxious feeling waiting for the end of the 4th month results for Peg. I had my first results at 20 weeks and it was very hard when my specailist told me that there had not been much reduction. I was advised to complete..
Hi, you probably don't know but I had chronic HepB and took Peg interferon and lamivudine as a combo and got rid of both antigens and developed both antibodies so I am a very lucky bunny. Peg interferon and lamivudine as a combination therapy were no..
Hi Ian,
That's really amazing. Does that mean you are basically totally cured and now have immunity from getting it again? If that is the case then that is such great news, I'm really pleased for you and I really am determined to try and get the s..
hi Ian,
you may not wish to dicuss this but I was just wondering what your viral load was when you started on the peg-lam combo?? There is growing evidence that certain combinations may in the end be better than sequential monotherapy.
I also imagi..
Hi Simon and Brit. I got antibodies nearly 3 years ago now. I was on the combo for 6 months and the antibodies started to appear well into the treatment and completed the two antibodies a few months after my treatment finished. I live near Glasgow an..
Hey Guys,
Hope your all well :o)
Just wanted to ask if anyone alse is on or has been on combo of Lamivudine and Adefovir?? Im on it at the moment. Has anyone had any proven results or heard of this combo???..
Hi Lily,
I'm on Lamivudine and Adefovir combo and it is definitely working for me at the moment. I was on both of them and my viral load went to undetectable. Then I came off Lamivudine and it went up (although not by much). And then 3 months ago..
Thanx Simon! Its good to know that. How long were you on it until your viral load came down. Apparently, before i started this treatment they couldn't gauge my viral load cos it was off the scales! I have my first follow up appointment in October, i'..
Hi,I have HepB friends in the States and they are having good results too...
HI Lily,
Actually within 3 months the viral load was undetectable. But, it didn't have to come down from very far since I had already been on single drug treatment for a while. All the consultants I've spoken to (which is quite a lot) reckon this ..
Hi Ian and Si,
Thanx for the encouragement. Its good to know this treatment has worked so well for people. I just hope its the same in my case as my viral load is extremely high! i'll let you all know in October when i get the results :o)
Take Care..
Hello everyone.
I found out I was HIV+ and had Hep-B back in May 2005. I found out later than I had Chronic Hep-B, and the last time I got any blood results from tests was told by my specialist in Leeds that my Hep-B viral load was around about 10^8..
Hi Steve! I have heard from friends in the States that tenofivir can be effective against HepB, although I do not know about a co-infection and not sure about the HepB dosage. If you can please add your ALT blood results when you post them on here as..
Hi, Ian
Here are the results of the tests I had back in April 2007.
I don't have my ALT for back then at the moment but will get it later today.
Hep-B Core Antigen - Positive
Hep-B Surface Antigen - Positive
Hep-B E-Antigen - Positive
Hep-B Cor..
Hi Everyone!
Just thought i would let you all know, i got a letter from the hospital today to say that my last results show that my hepatitas B D A was undetectable and more importantly, i have lost the hepatitas E antigen and produced an antibody!!..
Hi Lily,
Fantastic news!! Getting the news of the antibodies must have been good (to put it midly) !! So pleased for you!
Do you mind me asking how high your viral load was (you said it was off the scales)?? I have always thought that my starting VL..
Hi Brit
Hope your doing well. Sorry to hear your results are so versatile lateley, but don't give up:o)
To be honest, i don't know how high the level was. My consultant told me they were unable to measure the levels when i started the peg interfero..
What great news Lily, I only just saw that you have an antibody, brilliant news.
Brit, do you mind me asking where you are being treated. I thought Entecavvir was still unavailable on the NHS here in the UK??
Simon..
Hi Simon,
I am being treated in the Netherlands. I was thinking that because the EU Medicines Agency had approved it in late 2006 that everyone in the EU would have access to it. It is still a case of local authorities budget co-ordinators deciding ..
Brit,
Thanks and good luck.
sm..
American here. Less than one year of Entecavir and undetectable HepB viral load. No antibody yet, but hoping. I have private health insurance with my employer. I am lucky because without insurance Entecavir is 700 USD/month. I pay 25 USD/month n..
hi USA
I am on entecavir too .....viral load down from 10 8 to 10 3....but specailist recently doubled the pills to try to get me to undetectable as viral load seemed to have plateaud (will do next test next month).......great that you are UND.
Vir..
Hello all! I am on entecavir too for 4 months now. This was prescribed by my doctor in the Philippines. Been here in the UK for more than 1 year and have seen my GP and Gastro specialist. Now, I have been referred to a liver specialist and still wait..